March Madness Sweet 16 Betting Preview

March Madness Sweet 16 Betting Preview

March Madness Sweet Sixteen Betting Preview

March Madness seems to get better every year, and the 2022 version has not disappointed. Some favorites have dominated, while others have been dumped out much sooner than expected. Every tournament needs a Cinderella, and Saint Peter’s is one of the most heartwarming underdogs in recent memory. This tournament has shown that anything can happen, and US bettors have had a great time trying to predict these games and sometimes making great profits.

The rounds of 64 and 32 were fantastic, but the round of 16 could be the sweetest one yet. With so much still left to play for, there could still be some shocks. That makes it very hard to make betting predictions. Don’t worry, we’re here to help! Our BestAppBet experts have taken a look at the sweet sixteen games to see which picks you should add to your bet slip this week. 

Arkansas vs. Gonzaga

Gonzaga seemingly makes runs in the tournament every year, and the Bulldogs have made it to at least the sweet sixteen in each of the last six tournaments. Before last season Arkansas had not made it past the second round of the NCAA tournament since 1998. The Razorbacks made a shocking run to the elite eight last year before losing to eventual national champion Baylor. 

You may think Gonzaga is the clear favorite, and the betting line shows the team as -9.5 on the spread with BetMGM. But in tournament basketball, elite guards typically lead teams on deep runs. Just ask Gonzaga about having top-five NBA draft pick Jalen Suggs running the show last year as it made the national championship game. Gonzaga boasts the better frontcourt, but Arkansas has enough size to contest with the Bulldogs’ bigs. 

Arkansas has a much better backcourt with three different guards averaging double figures. Expect this game to be close, but Arkansas guard play will find a way to make the winning plays down the stretch. That’s why we’re backing Arkansas to cover the +9.5 spread.

Michigan vs. Villanova

No one is shocked that Michigan basketball finally found a way to get this talent roster to play its best basketball. Barely finding its way into the tournament field as an 11 seed, the Wolverines have pulled off back-to-back upsets to make it this far. Its upset over Tennessee impressed a lot of bettors as many had the Volunteers to win the national championship. 

However, Villanova is a different story and has one of the best coaches in the country in Jay Wright. He knows what a deep tournament run looks like, and Wright can coach circles around Juwan Howard of Michigan. Bookmakers agree with Villanova -5 on the spread with DraftKings. We expect Villanova to be much more disciplined and have a much better game plan after multiple days of preparation, making it an easy pick to come out on top. 

Texas Tech vs. Duke

The Duke Blue Devils hope to send legendary coach Mike Krzyzewski out with one last national championship on his farewell tour. That’s the fairytale for the Blue Devils, but don’t expect it to happen. Duke boasts as much talent as anyone in the tournament but has shown that it’s very beatable. In fact, if not for a big game from soon-to-be top-five NBA draft selection Paolo Banchero, Duke wouldn’t have survived the second round. 

Duke now comes up against Texas Tech, a team loaded with veteran players and one of the country’s best defenses. We think the Blue Devils will come up short when they need big plays. It takes an incredibly rare group to make a deep run with a team full of freshmen and sophomores. While Duke is exciting for recruiting rankings, veteran teams like Texas Tech usually win big games late in the season. Despite this, Texas Tech is only a -1 favorite on the spread. We suggest picking experience over youth and taking this betting line. 

Houston vs. Arizona

Arizona has been a surprise team this year, with not many backing it to reach the sweet sixteen stage. After getting rid of long-time coach Sean Miller, the hire of Tommy Lloyd seems like a perfect fit. Arizona has always been loaded with talent, with Miller being known as a great recruiter, even if his methods were sometimes questionable. However, Miller was never a great in-game X’s and O’s coach. In contrast, Tommy Lloyd, after serving under Mark Few at Gonzaga for 22 years as an assistant, is a fantastic in-game coach. Lloyd inherited great talent, but his coaching has raised the team’s ceiling, possibly to championship heights. 

Houston has become a yearly mid-major team that makes solid runs in the tournament. Houston has made the final four and the sweet sixteen in the last two seasons before this one. While Houston is a solid team, expect Arizona to come away with this one. The spread shows how close this one is, favoring Arizona at -1.5. This could go right to the wire, so perhaps the moneyline is the way to go.

Saint Peter’s vs. Purdue

The Saint Peter’s Peacocks are this year’s Cinderella team after shocking the world-beating, heavily favored Kentucky in the opening round of the NCAA tournament. The team proved it was more than a one-hit-wonder by following that up by beating an outstanding  Murray State team. Murray State finished the season with a 31-2 record compared to the Peacock’s 20-11.

On the other, Purdue is a traditional power five team that is very good but has been prone to upsets this season. The Boilermakers have a considerable size advantage but may struggle with the balanced attack of the Peacocks. Saint Peter’s doesn’t boast any single star player averaging a ton of points but has nine players scoring anywhere from 4.3 ppg to 11.4 ppg. No other 15 seed has made it past the sweet sixteen in tournament history, but there is just something unique about this Peacock team. Despite BetMGM having the team at +12.5 on the spread, we’re following our hearts and expect Saint Peter’s to win once again.

Providence vs. Kansas

This one is simple. While a very good basketball team, Providence is running into an outstanding Kansas team at the wrong time of the year. Kansas may have the best guard trio in the country in Ochai Agbaji, Christian Braun, and Remy Martin. Not only that, Agbaji and Martin are seniors, and Braun is a junior. This trio has looked like they are on a mission and expect the team to win and cover the -7.5 spread.

North Carolina vs. UCLA

A matchup of traditional blue blood teams dating way back, this game has all the history any basketball fan could want. North Carolina pulled off an upset of defending national champion Baylor last weekend, yet it almost let a 20 plus point lead slip away. The Tar Heels squeezed through in overtime. 

While UCLA has had an up and down year, it has a roster filled with veterans. The team kept pretty much everyone that made it to last year’s final four. The Bruins look like the best team left in its region and we expect it to find a hot shooting streak halfway through the second half to pull away from the Tar Heels. Backing the over at 141.5 could return a tidy profit if UCLA gets going. 

Iowa State vs. Miami

No matter what the result of the game is, one thing is guaranteed from this matchup: There will be at least one double-digit seed in the elite eight. The difference is that Iowa State has beaten an LSU team in the middle of all kinds of drama and scandal. Then it beat a Wisconsin team that saw one of their best players in Chucky Hepburn go down injured in the first half. On the other side, Miami has outplayed and beaten two excellent teams in USC and Auburn. While this one should be close, as Miami only has a -2.5 advantage on the spread, we think the Hurricanes will win by three points or more.

Betting on March Madness in the US

The great thing about March Madness is no one knows what’s coming next! So while our experts have picked out great tips, you can bet on pretty much any market you want online in many US states. Since 2018, when the US Supreme Court struck down the PASPA, states have been legalizing online sports betting.

States have different rules when it comes to college betting. Some restrict wagers on in-state teams or betting on player props. Others, like Pennsylvania, don’t have any restrictions on college betting at all. Be sure to check the laws of wherever you are playing. If you are in a state with legalized online sports betting, you can download a sportsbook app and place wagers on March Madness today!

Share on facebook
Share on twitter
Golden Nugget Logo
Golden Nugget
Being one of the top casinos in the USA, Golden Nugget are now offering Americans one of the best online casino and sportsbooks for the newly-regulated US online casino and sports betting market. Visit Golden Nugget’s website and download their sports betting app, and within minutes you too can be playing and betting in one of the world’s top casinos – all from the comfort of your own home.
Sugar House Casino Logo

Sugarhouse is owned by Rush Interactive, which is one of the most prominent providers of online sportsbook and casinos in the country. In 2016, SugarHouse launched it online casino in New Jersey, joined by its online sportsbook in 2018. Since then, it became a leading casino and sportsbook for Americans. Check out their fantastic bonuses, games and bets available, and see yourself why when it comes to casino and sports betting in the USA, Sugarhouse is a Powerhouse 

Resorts Online Casino
Resorts Atlantic
Partnered with Resorts Atlantic City Casino, the Resorts online sportsbook and casino launched in January of this year, and has since been making headways in the race to the top of online sports betting operators in the USA. Just like the Resorts Casino in Atlantic City, Resorts brings online and in its sports betting mobile app everything of top market standard: bonuses, odds, betting markets, types of bets and more.


March Madness Sweet 16 Betting Preview

March Madness seems to get better every year, and the 2022 version has not disappointed. Some favorites have dominated, while others have been dumped out much sooner than expected. Every tournament needs a Cinderella, and Saint Peter’s is one of the most heartwarming underdogs in recent memory. This tournament has shown that anything can happen, and US bettors have had a great time trying to predict these games and sometimes making great profits.

Read More »

March Madness Betting Favorites

With February officially coming to an end, NCAA basketball fans are gearing up for perhaps the biggest March Madness in recent memory. Now more than ever before, there seem to be upset every weekend. Not only that, but college basketball betting has also grown exponentially in the past twelve months since the Baylor Bears won their first national championship in program history. With the hype now starting to build and Selection Sunday less than a month away, sports pundits have been speculating who they believe will bring home the trophy in 2022.

Read More »

March Madness Betting Guide

December has Christmas, January has New Year’s Day, February has Valentine’s Day, and March has March Madness. The time has almost come for the US’ favorite college sports tournament. The nation’s full attention falls on those teams that qualify for the tournament. Over the years, millions of Americans have taken part in local brackets on who will win March Madness.

Read More »


Sports betting has always been an exciting way for fans to buy into the sport, in a way participate and add another dimension of thrill and excitement to the competition, match or any sporting event. With the evolution of remote betting first to phone, and later on to online betting, remote sports-betting not only became available to a wider audience, but also added a whole new level of excitement and magic to sports betting. Today’s mobile sports betting apps, which are readily available on both Android and Apple, are on the front line of technology, and alongside an exceptional slick and user friendly interface, opens to sports betting punters an entire universe of sports events, odds, games and features such as live streaming and in-play betting. Are you into NFL? Are you an NBA fan? Maybe your thing is baseball so you would like to bet on MLB? Or perhaps you are into world sports and want some European Premier Soccer betting? The mobile sports betting apps bring all of this amazing action to your mobile device, so you can bet on what you want, from wherever you are, at any time you choose to.


Are you a casino player? Did you always love casino, the atmosphere, the thrill and excitement, and most importantly the dream and sometimes reality of big winnings? You no longer need to wait for your next trip to Vegas, or wherever it is you are planning to go to a casino. Mobile and remote casino gambling has now entered to US, and it is here to stay. Already live in New Jersey, and closely followed by other states, Americans can now join the fun, download a casino mobile app from one of the top, legal and certified US casinos, and have all the magic of casino from their mobile device. Are you a BlackJack player? Or maybe you are into Roulette? Maybe Baccarat or Craps are your game, or are you a fan of slots? Whichever game is for you, you will find it on the mobile casino apps that are now becoming legal and regulated across states, and enable you to have your own private casino on your mobile device. It is legal, it is exciting, and it is magic.


For many, slot machines are the most thrilling part of the casino. The lights, animation, sounds and action take you into another dream world, where you can win huge prizes, jackpots, bonus rounds and what not. The Mobile slot apps that are now available in the US provide the world’s premier slots, all made regulated and fully compliant with the US regulations and laws. So you can safely and securely download the slots mobile app to your mobile device (where it is legal to do so), and have the most amazing slot game experience coming to life on your mobile phone. Are you into progressive slots where you get a chance at winning an amazing jackpot, or perhaps you are into an animated video slot that has branded content with your favourite movie, TV or music stars? All of these amazing titles are just a swipe away, all available on your mobile phone by downloading the mobile slot game app.     


A lot has changed since the first games of poker were played along the Mississippi River in the 1800s, with Poker becoming a worldwide phenomenon, crossing the boundaries of a card game and considered by many a sport, with tournaments, leagues and champions. Being a game with friends or a professional tournament, the online revolution turned poker to be a game that is played and followed by billions all over the world. And then the latest stage of the poker uprising which is the mobile poker apps, which enable you to access any kind of level, tournament and game from your mobile phone, no matter where you are in the world, and what time it is, you can join in the poker fun and excitement and play against other poker enthusiasts like you around the globe. Poker is now coming home again, and becoming legal to play remotely state after state in the USA also. So now Americans can already download a safe and legal mobile.